Ibutilide Fumarate, Injection

Type of medicine: antiarrhythmic

Generic and brand names: ibutilide fumarate, injection; Corvert

This medicine is given by IV infusion (slow drip through a needle into a large vein) to treat irregular heartbeats. This treatment may be lifesaving.

Before taking this medicine, tell your health care provider if you have ever had an allergic reaction to any medicine. Also tell your provider about all the other medicines you take.

Females of childbearing age: Talk with your health care provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your health care provider's approval.

These injections are given by a health care provider in a hospital.

Health care providers will constantly monitor your response to this medicine. The dosage will be adjusted depending on your response.

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your health care provider if you have any side effects that continue or get worse.

Serious (report these to your health care provider): Fast, pounding, or irregular heartbeat; chest pain or discomfort.

Other: Headache, nausea, feeling faint.

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your health care provider if you are taking:

• antibiotics such as gatifloxacin (Tequin), moxifloxacin (Avelox), sparfloxacin (Zagam), erythromycin (Ery-Tab, E-mycin), and clarithromycin (Biaxin)
• antipsychotic medicines such as chlorpromazine (Thorazine), fluphenazine (Permitil, Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), promazine (Sparine), thioridazine (Mellaril), trifluoperazine (Stelazine), and ziprasidone (Geodon)
• other medicines to treat irregular heartbeat such as amiodarone (Cordarone, Pacerone), procainamide (Pronestyl), disopyramide (Norpace, Norpace CR), quinidine (Quinidex, Quinora, Quinaglute, Cardioquin), sotalol (Betapace), dofetilide (Tikosyn), flecainide (Tambocor), lidocaine (Xylocaine), and tocainide (Tonocard)
• tricyclic antidepressants such as amitriptyline, amoxapine, clomipramine, desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), and nortriptyline (Aventyl, Pamelor)
• digoxin (Digitek, Lanoxin).

Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all health care providers who treat you about all the products you are taking.

This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your health care provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.

Do not share medicines with other people.